Kelly Ryan Gallagher

Work:  Dept. of Chemistry & Biochemistry

  SUNY- College at Oneonta

  Oneonta, NY 13820

  (607) 436-3180

Home:   P.O. Box 124

 34 Monitor Street

 Schenevus, NY 12155

 (607) 638-5062

E-mail:  gallagkr@oneonta.edu

EDUCATION

á          Ph.D., Biochemistry & Molecular Biophysics, March 2002, Univ. of Pennsylvania, Philadelphia, PA

Advisor: Dr. Kim A. Sharp

Thesis Title: ÒElectrostatic Contributions to Heat Capacity Changes and an Analysis of Thermal Hysteresis Protein Hydration Using the Random Network ModelÓ

á          B.Sc. in Biochemistry, May 1990, Boston College, Chestnut Hill, MA

Advisor: Dr. Evan R. Kantrowitz

Thesis Title: ÒDevelopment of Auxotrophic E. coli Strains and Production of Labeled Aspartate Transcarbamoylase for Structural StudiesÓ

PROFESSIONAL INTERESTS

á          Thermodynamics of solvation in biochemical systems

á          Biochemistry of organisms in extreme environments

á          Computer modeling of biochemical systems

á          Science education and teacher education

PROFESSIONAL EXPERIENCE

á          August 2007 to present

Assistant Professor,  Department of Chemistry and Biochemistry

State University of New York College at Oneonta, Oneonta, NY

Taught large enrollment (~200 students) non-majors General Chemistry course, coordinated and managed laboratory sections, maintained course web site. Taught upper level Biochemistry course (with lab) and introductory chemistry labs.

 

á          January 2006 May 2007

Lecturer, Department of Chemistry and Biochemistry

State University of New York College at Oneonta, Oneonta, NY

Taught large enrollment (~200 students) non-majors General Chemistry course, coordinated and managed laboratory sections, maintained course web site. Taught upper level Biochemistry course (with lab) and introductory chemistry labs.

á          August 2003 to present

Assistant Director

Science Discovery Center at Oneonta, Oneonta, NY

Assist in the maintenance and operation of the Center, including preparation of materials leading to the award of a $100,000 state grant, exhibit design and maintenance, and hosting of elementary school groups. Organized and presented at the workshop ÒPreparing for the New York State Elementary Science ExamÓ in cooperation with the Catskill Regional Teacher Center (June 2004).

á          September 2002 to 2008

GRE Reader

Educational Testing Service, Princeton, NJ

Evaluate written responses to the analytical writing portion of the Graduate Record Examination.

á          May to September 2005

Freelance Science Writer

Words & Numbers, Inc., Baltimore, MD

Reviewed online educational videos for content accuracy, prepared quizzes, identified key curriculum concepts and key word lists for Discovery Education Science (Content areas: biology, chemistry, and physics; Grade levels: K-12).

á          Spring 2003

Adjunct Lecturer, Department of Physics and Astronomy

State University of New York College at Oneonta, Oneonta, NY

Taught algebra-based general physics lecture and laboratory; developed laboratory experiments.

Reviewed the college text Biomedical Applications of Introductory Physics, by Jack Tuszynski and John Dixon, for John Wiley & Sons.

á          Spring 1998 & 1999

Teaching Assistant, Department of Biochemistry and Biophysics

University of Pennsylvania, Philadelphia, PA

Aided in the development of computer tutorials for the course ÒMacromolecular Modeling and Structure Analysis,Ó created supplementary material on UNIX, modeling software packages, and docking techniques; assisted students with tutorials and final term projects.

á          Fall 1996-1998

Lead Teaching Assistant, Department of Biology

University of Pennsylvania, Philadelphia, PA

Taught introductory molecular biology laboratory for majors; composed problem sets and exam questions; graded exams and lab reports; organized and ran exam review sessions; coordinated and trained teaching assistants for the course ÒMolecular Biology of Life

á          Spring 1995

Teaching Assistant, Department of Biology

University of Pennsylvania, Philadelphia, PA

Composed exam questions; graded assignments; presented exam review sessions for the non-majors biology course, ÒHuman Biology

RESEARCH EXPERIENCE

á          March 2002-December 2002

Postdoctoral Fellow

August 1994-March 2002

Graduate Student in Biochemistry and Molecular Biophysics

University of Pennsylvania, Philadelphia, PA

Created FORTRAN routines to improve the precision of Finite Difference Poisson-Boltzmann electrostatic calculations; developed technique for calculating electrostatic contributions to heat capacity changes; studied heat capacity changes in DNA binding reactions; developed program for analysis of macromolecular hydration structures; studied the structural and thermodynamic consequences of antifreeze protein hydration; helped maintain departmental computer modeling facilities.


á          August 1990 to August 1994

Research Associate, Molecular Biology

Repligen Corporation, Cambridge, MA

Developed phage display libraries; studied mechanisms of cytokine-receptor binding using a variety of biochemical techniques; cloned native and mutant proteins in mammalian, baculoviral, E. coli, and phage systems; developed stable cell lines expressing wild type and mutant HIV envelope proteins; responsible for scale-up and large scale fermentation development of recombinant E. coli strains.


 

á          September 1988-May 1990

Undergraduate Research Assistant, Department of Chemistry

Boston College, Chestnut Hill, MA

Developed E. coli expression and purification systems for several enzymes; devised analytical gel chromatography technique for studying the structural properties of wild type and mutant enzymes; developed an auxotrophic E. coli strain to facilitate the study of enzyme structural transitions via 13C NMR.

á          Summers 1987 to 1989

Summer Intern, Department of Anti-Infective Microbiology

Bristol-Meyers Squibb, Wallingford, CT

Studied mechanisms of host response to bacterial infection; assisted in the development of drug screening assays; aided in the maintenance of microbial culture collections.

PUBLICATIONS

(2004) Modern Chemistry 2006 (Holt, Rinehart, & Winston). Wrote and edited ancillary materials for advanced high school chemistry text, including the preparation of section reviews, section quizzes, and chapter tests.

Kelly Gallagher and Kim Sharp.  (2003)  A New Angle on Heat Capacity Changes in Hydrophobic Solvation.   J. Am. Chem. Soc., 125: 9853-60.

Kelly Gallagher and Kim Sharp.  (2003)  Analysis of Thermal Hysteresis Protein Hydration Using the Random Network Model.  Biophysical Chemistry, 105:195-209.

Kelly Gallagher and Kim Sharp.  (1998)  Electrostatic Contributions to Heat Capacity Changes of DNA-Ligand Binding.  Biophysical Journal, 75(2): 769-776.

Kashi Javaherian, Alphonse J. Langlois, David C. Montefiori, Karen A. Kent, Kelly A. Ryan, Peggy D. Wyman, James Stott, Dani P. Bolognesi, Michael Murphey-Corb, and Gregory J. LaRosa.  (1994).  Studies on the Conformation-Dependent Neutralizing Epitopes of the SIVmac Envelope Protein.  J. Virol., 68(4):2624-31.

PRESENTATIONS

James Lauzun and Kelly Gallagher. Investigation of the Hydration Structure of the Snow Flea Antifreeze Protein. American Chemical Society 235th National Meeting, April 2007.

Kelly Gallagher and Kim Sharp.  Examining the Structure of Water Around Proteins.  13th Annual Gibbs Conference on Biothermodynamics, October 1999.

Kelly Gallagher, Bhupinder Madan, and Kim Sharp.  Structural Analysis of the Water Hydrogen Bonding Network Around Antifreeze Proteins.  12th Annual Gibbs Conference on Biothermodynamics, October 1998.

Kelly Gallagher.  Examining the Sources of Heat Capacity Changes.  University of Pennsylvania Dept. of Biochemistry & Biophysics Annual Retreat, Swarthmore, PA, July 1998.

Kelly Gallagher and Kim Sharp.  Electrostatic and Structural Contributions to Heat Capacities of Binding and Solvation.  11th Annual Gibbs Conference on Biothermodynamics, October 1997.

Kelly Gallagher and Kim Sharp.  Electrostatic Contributions to Heat Capacity Changes Upon DNA Binding.  Biophysical Society Annual Meeting, March 1997, and Protein Society Annual Symposium, July 1997.

PROFESSIONAL AND RELATED MEMBERSHIPS

American Chemical Society

Biophysical Society

Schenevus Central School Board of Education (Chairperson, Audit Committee)