Dr. Terry L. Helser, Professor of Chemistry
227 Physical Sciences Building, Oneonta, NY 13820-4015
Phone: (607)436-3518 or Email to:
Study Guide - Biochemistry, The Molecular Basis of Life, 4th Ed., 2009, T. & J.R. McKee (Oxford Univ. Press)

Chapter 11: Lipid Structure

You can go back to the Fall, Spring or Summer schedules, to information on the lab , to the extra credit puzzles , or leave me a message . Or skip to ß Oxidation section. 

How are lipids defined? What are fatty acids? Describe their 2 part structures.

What are complex and simple lipids? Give examples of each.

How do saturated and unsaturated fatty acids differ? Which are essential? Why are they essential?

Name the common C16 and C18 fatty acids. Why are they not found free in the body?

What molecules form a triacylglycerol? What is their function in the body? What is their hydrolysis reaction called and what does it produce?

What molecules form a phosphoacylglycerol (phosphoglyceride)? What is their function in the body?

Name and state the function of important steroids and sterols .

What types of lipoproteins are there? What determines their density? What is their role in atherosclerosis? How are LDL receptors relevant here?

Note Biochemical Connections, pp. 195, 198, 207 & 212.

End of chapter questions: 1.-3., 7.-9., 11.-16., 17.-45.  

You can get back to Lipid Structure .
Chapter 12: ß Oxidation of Fatty Acids

How are stored fats mobilized for oxidation?

Where and how are fatty acids activated prior to ß oxidation? How many ATP equivalents are used?

How are acyl-CoAs transported to the site of ß oxidation ? Where is that?

What is produced during one cycle of ß oxidation? How many ATP equivalents are produced?

How many cycles are needed to completely metabolize palmitate ? ...stearate?

What reactions in ß oxidation are equivalent to reactions (which?) in the Krebs Cycle? Which is unique?

What is the net yield of CO2, H2O and ATP (how many of each?) from palmitate?

Of what importance is the production of metabolic water to the camel or kangaroo rat?

What is the relationship between cholesterol and bile? What genetic diseases result from defects or dietary excesses in fat metabolism?

Note Biochemical Connections p. 579. End of chapter questions: 1., 4.-13.

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