Introductory Biochemistry
CHEM 330-01 (CRN 119)
CHEM 330-02 (CRN 120)
CHEM 330-03 (CRN 121)
| Class, Test Schedule |
(Room: HECO 132; M,W,F 9 AM) |
Fall, 2008 |
| Instructor: Dr. Terry L. Helser |
Office: PS 227 |
Phone: 607-436-3518 |
E-mail To: HELSERTL@oneonta.edu.
Text: Biochemistry, 4th Ed., 2008, T. & J. McKee
(Oxford Publishers)
Catalog Description: A survey of the basic biochemistry
one needs to understand recent medical and biotechnological advances. The
structure and functions of molecules and macromolecules in energy and genetic
metabolism are studied. (LA Z) Prerequisite: CHEM 226 or 221.
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the grade scale , or to the bottom
of the page for addresses and other options. You also can move to the lab
schedule , the lab grading information, and the general
information
on
lab operation. Study guides are linked to the reading assignments.
Class Schedule
| Month & Days |
Study Topic |
Reading Assignment |
|
I. Life's Structure |
Autobiography |
|
August 27,29 |
Introduction, Co-op Class |
Ch.
1 |
|
September 1,3,5 |
Cells, Atoms & Bonds
|
Ch.
2 |
|
8,10,12 |
pH & Water
|
Ch.
3 |
|
15,17,19 |
Amino Acids (Model Building)
|
Ch. 5
|
22, 24 |
Protein Structure |
|
|
26 |
Exam I (Friday, HECO 132, 9 AM)
|
Ch.
4,6 |
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|
Month & Days |
II. Energy Metabolism |
Reading Assignment |
|
29, October 1, 3 |
Enzymes & Energy |
Ch. 6
|
|
6, 8 |
Enzyme Kinetics |
Ch.
6 |
October 10 |
Fall Break - No Classes, Labs |
|
|
13, 15, 17 |
Metabolism of Sugars |
Ch.
7 |
|
20, 22, 24 |
Krebs Cycle, Electron Transport
|
Ch. 8, 9
|
|
27, 29 |
Ox. Phosphorylation
|
Ch. 10 |
|
October 31 |
Exam II (Friday, HECO 132, 9 AM)
|
Ch.11 |
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|
Month & Days |
III. Genetic Metabolism |
Reading Assignment |
|
November 3, 5, 7 |
Lipid Structure, ß Oxidation |
Ch.
12 |
|
10, 12, 14 |
Nucleic Acids |
Ch. 17
|
|
17, 19, 21 |
Replication
|
Ch. 18.1, 18.2
|
|
24-28 |
Thanksgiving Vacation - No Classes
|
|
|
December 1, 3, 5 |
Transcription & The Genetic Code
|
Ch. 19
|
|
8, 10, 12 |
Translation & Control of Gene Expression |
Ch. 18.3 |
|
December 17 |
Final Exam (Wednesday, HECO 132,
|
8 - 10:30 AM) |
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Grading
|
Hourly Exams
|
2 x 100 pts. = 200 pts.
|
Scale: 90-100% A
|
|
Final Exam
|
200 pts.
|
80-89% B
|
|
Lab Research Paper
|
100 pts.
|
70-79% C
|
|
Laboratory Evaluations
|
200 pts.
|
60-69% D
|
|
Total: 700 pts.
|
0-59% E
|
You may earn up to 35 points for extra credit problem sets given throughout
the semester. Tests have 10% more points than listed so I can challenge
the best.
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Laboratory Schedule (Room:
PSci 205 - Thr./Fri 2-5 pm) Fall, 2008
Required Materials: Graph Ruled Lab Notebook, Safety Goggles
You can go to the second or third
part of the lab schedule, lab grading procedures or general
information
on lab time management from here.
|
Month & Days
|
Laboratory Topic
|
Evaluation (Due Date)
|
|
August 28, 29
|
Form Groups, Check In, Plan Buffer
|
1-Oral Progress Rpt.
Quiz (?)
|
|
September 4, 5
|
#1 Buffer
Experiments
|
1-Prop (draft 9/3)
|
|
11, 12
|
Buffer
Experiments
|
1-Proposal (9/10) |
|
18, 19
|
Buffer Reports
#2 Enzyme
Catalyzed Reactions
|
1- Oral Rpt.
, Peer Eval.
2-Oral Progress Rpt.
|
|
25, 26
|
Enzyme Catalyzed
Reactions
Enzyme Reactions, Specificity
|
1-Final Report (9/26, 10/3)
2-Proposal (9/25) |
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|
Month & Days |
Laboratory Topic |
Evaluation (Due Date) |
|
13, 14 |
Enzyme Purification
#4 ImmunoAssay |
-
3-Oral Rpt. , Peer Eval.
-
3-Final Rpt. (11/12)
|
|
20, 21
|
ImmunoAssay |
4-Proposal (11/19) |
27, 28 |
No Labs - Thanksgiving Break |
|
|
December 4, 5 |
ImmunoAssay
|
4-Proposal (12/3) |
11, 12 |
ImmunoAssay
The Gene Game (Check Out)
|
4- Oral Rpt. , Final Rpt. (12/17) |
|
December 17 |
Final Exam (Option, Monday, HECO 138, |
11 - 1:30 PM) |
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Lab Grading Policies:
Departmental policies apply to this course, except where modified or expanded below:
Your point total will be divided by the total possible for a % of 200 points.
The final report for which you were primary author is worth a maximum of
100 points of your total grade.
Final reports must be typed, spaced ≥1.5 lines, and signed by all
group members. They must contain an objective, introduction, procedure
(flow diagram?), safety notes, results (an essay w/ tables, plots), discussion/conclusion,
and reference sections. The weekly proposals, with objective, equipment
and reagents needed, procedure (flow diagram), safety notes and references,
which proves you are prepared to do each experiment safely, must
be accepted by your instructor before you will be allowed to do the
lab ( submit an email no later than the Wednesday before the lab). One
point /day will be subtracted for reports submitted after due dates.
Oral reports are awarded ≤100 points,
of which 80% is for the group's presentation and 20% for the individual's
stage presence, poise and participation. Generally, the score is an average
of the peer evaluations from other teams and the instructor's. Copies of
the printed grading form are available in the laboratory.
Lab notebooks may be collected at the instructor's whim.
Please note: You are to use your notebook to prepare for each
lab with suitable notes on procedures, flow charts, tables for data,
etc.; to make notes and take data during the lab; and to do calculations
and write your results and conclusions after the lab. Each of
these parts will be evaluated.
Attendance:
You must be credited as the major author of at least 1 lab report and score
60% on lab evaluations to pass the course. If you miss more than 1/3 of
the labs, you will earn an E for the course, no matter what your
test scores total. Plagiarism (see your Handbook ) will not
be tolerated.
Safety:
Approved clothing and safety goggles must be worn when any
experimental work is occurring. Doing unauthorized experiments or procedures
is prohibited. If in doubt, ask the instructor. All accidents involving
personal injury, however minor, must be reported immediately to the instructor.
The instructor has the right to expel anyone from the laboratory without
credit for unsafe or offensive behavior or dress.
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Introductory Biochemistry, Chemistry
330 Lab Information
1st Week, Thursday/Friday lab:
-
Oral (group) report from prior project in 1st part.
-
Receive and study the next project. Groups work on the procedures
and techniques they will need, including doing trials with known materials.
-
Last 1/2 hour, teams do oral brainstorming as a lab group on how they will attack
the problem. Turn in requests for materials, equipment needed.
2nd Week:
- On Wednesday, submit the group's proposal for
the problem (objective (why), materials and equipment needed, procedure,
flow chart (how), safety and how to handle data) by e-mail.
Must be accepted by management before you can do the lab! - 1 point/day
off project total for late or inadequate proposals.
-
Also on Wednesday, turn in typed, final report on any prior project. (Each member of the group signs it to affirm they proofread it and
accept responsibility and credit earned for the work ≤ 100 points).
Clearly state the primary author.
-
On Thursday or Friday: Do the experimental work in the laboratory.
Turn in notebooks at end of lab, if requested.
-
Provide the whole group with a progress report about the project at end of
lab, if requested.
4th Week:
-
On Wednesday, submit the group's proposal for the
lab, if needed, by e-mail. Must be accepted by management before
you can do the lab! - 1 point/day off project total for late or inadequate
proposals.
Week after experiments are completed:
-
On Thursday or Friday, give oral report
on results (peer groups and instructor evaluations averaged ≤ 100 points.
Both individual and group contributions evaluated). Use feedback from forms
and other team reports to produce a final, group report.
-
On the following Wednesday, turn in typed, final report on project
(each member of the group signs it to indicate they have proofread it and
accept responsibility and credit for the work ≤ 100 points). Clearly state
the primary author of the report. Spelling and grammar will be evaluated
along with content.
Grading:
Oral (group) report ≤ 100 points
Group's proposal; Emailed by Fri. ≤ 10 points
Final reports ≤ 100 points
Notebook, Quiz ≤ 10 points each
- 1 point/day late off project total = % of 200 points
total
Final reports earn up to 100 points for the primary
author out of the 300 point total for the lab part of the course. S/he
must
be clearly identified on the first page, and each member must be
the primary author on at least one final report. A separate grade may
be given for the primary author's work.
If you must miss a class, lab or group meeting, you must inform your
group and instructor. Your group should decide on how you can repay your
responsibilities to the group. Options might be to do extra library research,
proposal or report writing, computer searches or whatever the group decides
is adequate repayment for the loss of your participation. If the group
decides your excuse was not valid, they may consider a loss of credit as
appropriate punishment, and should so inform you and the instructor.
Team members who fail to participate adequately with their team may
be fired, and justification must be provided to them and the instructor.
The member must then find a new team to hire him/her or do the projects
on their own, including all reports and proposals.
Penalties, generally -1 point a day for group reports which are late,
will be assessed against the primary author of that report, not the rest
of the group members, if requested by the group in writing or by email.
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If you have questions or comments, write the:
Author of this page: Terry Helser - helsertl@oneonta.edu
Web Coordinator: Philip S. Bidwell - bidwelps@oneonta.edu
Or return to the SUNY @ Oneonta Home
Page to see where we live and work.
Last Modified on 7/16/2008

