Catalog Description: A survey of the basic biochemistry one needs to understand recent medical and biotechnological advances. The structure and functions of molecules and macromolecules in energy and genetic metabolism are studied. (LA Z) Prerequisite: CHEM 226 or 221.

Click on the highlighted text to move directly to sections 1 , 2 or 3 of the class schedule, to the grade scale , or to the bottom of the page for addresses and other options. You also can move to the lab schedule , the lab grading information, and the general information on lab operation. Study guides are linked to the reading assignments.

Class Schedule

Month & Days	Study Topic	Reading Assignment
	I. Life's Structure	Autobiography
August 25,27	Introduction, Co-op Class	Ch. 1
30, September 1,3	Cells, Atoms & Bonds	Ch. 2
6,8,10	pH & Water	Ch. 3
13,15,17	Amino Acids (Model Building)	Ch. 5
20,22	Protein Structure
24	Exam I (Friday, HECO 132, 9 AM)	Ch. 4,6

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Month & Days	II. Energy Metabolism	Reading Assignment
Sept. 29, Oct. 1	Fall Break - No Classes, Labs
27, October 4	Enzymes & Energy	Ch. 6
6, 8	Enzyme Kinetics	Ch. 6
11, 13, 15	Structure, Metabolism of Sugars	Ch. 7. Ch. 8
18, 20, 22	Krebs Cycle, Electron Transport	Ch. 9
25, 27	Ox. Phosphorylation	Ch. 10
October 29	Exam II (Friday, HECO 132, 9 AM)	Ch.11

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Month & Days	III. Genetic Metabolism	Reading Assignment
November 1, 3, 5	Lipid Structure, ß Oxidation	Ch. 12
8, 10, 12	Nucleic Acids	Ch. 17
15, 17, 19	Replication	Ch. 18.1, 18.2
22-28	Thanksgiving Vacation - No Classes
29, December 1, 3	Transcription & The Genetic Code	Ch. 19
6, 8, 10	Translation & Control of Gene Expression	Ch. 18.3
December 15	Final Exam (Wednesday, room HECO 132,	8 - 10:30 AM)

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Grading

Hourly Exams	2 x 100 pts. = 200 pts.	Scale: 90-100% A
Final Exam	200 pts.	80-89% B
Lab Research Paper	100 pts.	70-79% C
Laboratory Evaluations	200 pts.	60-69% D
	Total: 700 pts.	0-59% E

You may earn up to 35 points for extra credit problem sets given throughout the semester. Tests have 10% more points than listed so I can challenge the best.

You can go to the second or third part of the lab schedule, lab grading procedures or general information on lab time management from here.

Month & Days	Laboratory Topic	Evaluation (Due Date)
August 26, 27	No Labs
31, September 2, 3	Form Groups, Check In, Plan Buffer	1-Oral Progress Rpt. 1-Prop (draft 9/3,7 or 8)
7, 9, 10	#1 Buffer Experiments	1-Proposal (9/10, 14 or 15)
14, 16, 17	Buffer Experiments
21, 23, 24	Buffer Reports #2 Enzyme Catalyzed Reactions	1- Oral Rpt. , Peer Eval. 2-Oral Progress Rpt.

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Month & Days	Laboratory Topic	Evaluation (Due Date)
28, 30, October 1	No Labs	1-Final Report (10/1) 2-Proposal (10/1, 5, 6)
5, 7 , 8	Enzyme Catalyzed Reactions	2-Proposal (10/8, 12, 13)
12, 14, 15	Enzyme Catalyzed Reactions	2-Proposal (10/15, 19, 20)
19, 21, 22	Enzyme Reactions #3 Enzyme Purification	2-Oral Rpt. , Peer Eval.  3-Oral Progress Rpt.
26, 28, 29	Enzyme Purification	2-Final Rpt. (10/22, 26, 27)  3-Proposal (10/22, 26, 27)
November 2, 4, 5	Enzyme Purification	3-Proposal (10/29, 11/2, 3)

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Month & Days	Laboratory Topic	Evaluation (Due Date)
9, 11, 12	Enzyme Purification #4Cholesterol Analysis	3-Oral Rpt. , Peer Eval. 3-Final Rpt. (11/12, 16, 17)
16, 18, 19	Cholesterol Analysis	4-Proposal (11/12, 16, 17)
23, 25, 26	No Labs - Thanksgiving Break
30, December 2, 3	Cholesterol Analysis	4-Proposal (11/19, 30, 12/1)
7, 9, 10	Cholesterol Analysis Report The Gene Game (Check Out)	4- Oral Rpt. , Final Rpt. (12/10, 13)
December 15	Final Exam (Wednesday, room HECO 132,	8-10:30 AM

• Oral (group) report from prior project in 1st part.
• Receive and study the next project. Groups work on the procedures and techniques they will need, including doing trials with known materials.
• Last 1/2 hour, teams do oral brainstorming as a lab group on how they will attack the problem. Turn in requests for materials, equipment needed.
• On Friday, the tuesday lab groups submit the group's proposal for the problem (objective (why), materials and equipment needed, procedure, flow chart (how), safety and how to handle data) by e-mail. Must be accepted by management before you can do the lab! - 1 point/day off project total for late or inadequate proposals.

• On T(Thr Labs) or Wed (F lab), submit the group's proposal for the problem (objective (why), materials and equipment needed, procedure, flow chart (how), safety and how to handle data) by e-mail. Must be accepted by management before you can do the lab! - 1 point/day off project total for late or inadequate proposals.
• Also on the next lab day, turn in typed, final report on any prior project. (Each member of the group signs it to affirm they proofread it and accept responsibility and credit earned for the work (≤ 100 points). Clearly state the primary author.
• On T, Th or Friday: Do the experimental work in the laboratory. Turn in notebooks at end of lab, if requested.
• Provide the whole group with a progress report about the project at end of lab, if requested.
• On Friday, the Tue lab groups submit the group's proposal for the problem (objective (why), materials and equipment needed, procedure, flow chart (how), safety and how to handle data) by e-mail. Must be accepted by management before you can do the lab! - 1 point/day off project total for late or inadequate proposals.

• On T(Thr Labs) or Wed (F lab), submit the group's proposal for the lab, if needed, by e-mail. Must be accepted by management before you can do the lab! - 1 point/day off project total for late or inadequate proposals.

• On T, Th or Friday, give oral report on results (peer groups and instructor evaluations averaged ≤ 100 points. Both individual and group contributions evaluated). Use feedback from forms and other team reports to produce a final, group report.
• On the following lab day, turn in typed, final report on project (each member of the group signs it to indicate they have proofread it and accept responsibility and credit for the work ≤ 100 points). Clearly state the primary author of the report. Spelling and grammar will be evaluated along with content.

If you must miss a class, lab or group meeting, you must inform your group and instructor. Your group should decide on how you can repay your responsibilities to the group. Options might be to do extra library research, proposal or report writing, computer searches or whatever the group decides is adequate repayment for the loss of your participation. If the group decides your excuse was not valid, they may consider a loss of credit as appropriate punishment, and should so inform you and the instructor.

Team members who fail to participate adequately with their team may be fired, and justification must be provided to them and the instructor. The member must then find a new team to hire him/her or do the projects on their own, including all reports and proposals.